Question: Which is an early sign of appendicitis? Pain localized to the right lower quadrant Nausea Fever Referred pain to the umbilical region AnorexiaWhich of the following is the most likely cause of global cerebral ischemia? Embolization of the internal carotid artery Hypotension resulting from acute blood loss Lipohyalinosis of small blood vessels Atherosclerosis of the middle meningeal artery Pulmonary thromboembolism