Allosteric enzymes are multi-subunit enzymes with "allo" or other sites, to which biochemicals may bind. When these biochemicals, or allosteric effectors, bind, they change the conformational structure of the enzyme, which, in turn, changes the activity of the enzyme. There are many allosteric effectors of allosteric enzymes in glycolysis, the TCA cycle, and gluconeogenesis. Choose 3 different biochemicals that act as allosteric effectors to influence 2 different metabolic pathways simultaneously, and for each allosteric effector describe:
c. The structural and functional consequences of the allosteric effector binding to the allosteric enzymes.
d. The metabolic consequence (i.e., what happens to the flux of the metabolic pathway) of the allosteric effector binding to the allosteric enzyme.