Pathology Assignment
Chapter 1:
• ICF Model (fill in your own example in hand out attached)
• Define:
o Health
o Illness; Acute vs. Chronic
- What is subacute illness?
o Disability: Physical vs. Cognitive
• What is the role of the PTA with health promotion and disease prevention?
• Psychologic aspects of Illness;
o Explain: Functional vs. Organic symptoms
• List 4 Benefits of exercise
• Genetic aspects of disease;
o What is the Human Genome project?
o What is Gene Therapy?
- List 5 uses of gene therapy
• Explain one approach to gene therapy
• What are some ethical concerns with gene therapy?
o What is gene doping?
• How is gene testing performed?
• What is the most important aspect for the PTA to understand about genetic disease?
• What is the difference between Compliance vs. Noncompliance?
• What is the most significant difference between DNA and RNA?
Chapter 3:
• Explain how age affects DNA
• What is the wear and tear theory?
o What are some cells that are impacted by this theory?
• What is the free radical theory?
• What is the telomere aging clock theory?
• What are the two types of cell injury?
• What are the mechanisms of cell injury?
o Three important concepts to understand:
- Immune reactions
- Genetic Factors
- Infectious agents
• What can cell injury caused by infectious agents' cause?
• What can cell injury caused by immune reactions lead to?
• What can cell injury related to genetic factors present as?
• Provide an example of a physical factor that may cause cell injury.
• How do chemical factors cause cell injury?
• How do psychosocial factors affect connective tissue?
• List 3 symptoms that can be seen with Vitamin C deficiency?
• List 3 factors that put a person at risk for Vitamin C deficiency?
• Explain the difference between ischemia and necrosis.
• The physical stress theory applies to all areas of physical therapy and is extremely important. Explain what you understand from mechanical factors and how they affect cell injury.
• What are the 4 components of tissue healing and what are their functions?
• Why is therapeutic ultrasound beneficial?
• What is the most important factor of tissue healing?
• Chose one factor that influences tissue healing and explain.
• What are the 4 phases of healing?
o BRIEFLY explain each
• What is a cytokine?
o Which two cytokines are most important, why?
• What is a tissue contracture?
• What is scar tissue? How long does it normally take a dense connective scar to form?
• Explain primary and secondary intention.
READ; Specific Tissue and Organ Repair
• What two types of tissue does bone consist of?
o What is the difference between these two?
• How do fractures heal?
• Give an example of EACH type of cartilage.
• Why does articular cartilage generate poorly or not at all?
• Where is the Menisci found? What is its principle function?
o See Fig 3.24 for types of tears
• What are the 3 principle functions of synovial fluid?
• Describe the three zones of the intervertebral disk.
• List 2 age-related changes that can occur to disks?
Format your assignment according to the following formatting requirements:
o The answer should be typed, using Times New Roman font (size 12), double spaced, with one-inch margins on all sides.
o The response also includes a cover page containing the title of the assignment, the student's name, the course title, and the date. The cover page is not included in the required page length.
o Also include a reference page. The Citations and references must follow APA format. The reference page is not included in the required page length.