Various treatments in patients with rheumatoid arthritis


Question: A study is designed to investigate whether there is a difference in response to various treatments in patients with rheumatoid arthritis. The outcome in patients self-reported effect of treatment. The data are shown below. Is there a statistically significant difference in the proportions of patients who show improvement between treatment 1 & 2. Apply the test at a 5% level of significance

1) Critical Value

2) Computed statistics

3) Based on comparing the computed statistics to the critical value which of the following is (are) true.

a) There is significant evidence, alpha = 0.05, to show that there is a difference in the proportions of patients who show improvement between treatments 1& 2.

b) There is not significant evidence, alpha=0.05 to show that there is a difference in the proportions of patients who show improvement between treatments 1 &2.

c) There is significant evidence, alpha =0.05, to show that there is a no difference in the proportions of patients who show improvement between treatment 1& 2.

d)  A & C

                         Symptoms worsened      No effect       Symptoms improved         Total

Treatment 1               22                              14                         14                           50

Treatment 2               14                              15                         21                           50

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Basic Statistics: Various treatments in patients with rheumatoid arthritis
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