Q1. When stained with the Giemsa dye, human mitotic chromosomes show a characteristic pattern of light and dark 'bands'. The human karyotype contains ~2000 G-dark bands that are visible in high resolution metaphase spreads. If the haploid human genome contains three billion base pairs and encodes ~30,000 genes, roughly how many genes would be removed by a DNA deletion that might be detected by karyotypic analysis?
Q2. What is the main difference between enveloped and nonenveloped viruses? How does this affect entry of each kind of virus into the host cells? Variances are expressed.
Q3. Histone H1 appears to play an important role in the formation of the 300 angstrom fiber, while the other histone proteins do not appear to participate. Why do you think this is true?