Discussion:
Biochemistry and Molecular Characteristics
Question #1:
In the urea cycle, the molecule that is synthesized in the cytosol and transported to the mitochondrial
matrix for subsequent reactions is
a.) citrulline
b.) ornithine
c.) argininosuccinate
d.) aspartate
e.) carbamoyl-phosphate
Question #2:
Inosine 5'-phosphate is a precursor to which nucleotide?
a.) adenosine 5'phosphate
b.) guanosine 5'phosphate
c.) cytidine 5'phosphate
d.) uridine 5'phopshate
e.) both a and b
f.) both c and d
Question #3:
PRPP can be used for production of which nucleotides?
a.) adenosine 5'phosphate
b.) guanosine 5'phosphate
c.) cytidine 5'phosphate
d.) uridine 5'phopshate
e.) all of the above
Question #4:
Fluoro-dUMP is an excellent chemical for chemotheraphy because:
a.) dTMP is a product of this reaction and dTMP is only required for DNA biosynthesis
b.) DNA biosynthesis only occurs in mitotically or meiotically active cells
c.) Fluoro-dTMP is an effective inhibitor of thymidylate synthetase
d.) thymidylate synthetase is required for dTMP biosynthesis
e.) all of the above