Proliferation of developing b cells


Assignment task:

Proliferation of developing B cells after heavy chain recombinations requires the presence of RAG-1 and RAG-2. results in production of many B cells with the same antigen specificity after the rearrangement of the L chains is complete. results in the production of many B cells with the same VH chain but different antigen specificities due to different VL regions. makes the developing B cells more susceptible to apoptosis if the pre-B cell receptor binds self antigen

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Biology: Proliferation of developing b cells
Reference No:- TGS03405583

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