Problem:
A 45-year-old female comes to the office reporting increased thirst, frequent urination and fatigue for the last 4-5 weeks. She reports blurred vision and occasional dizziness. The patient report that she has recently gained some weight and leads a sedentary lifestyle. She has a family history of type 2 diabetes. Physical Examination: ? BP: 140/85 mmHgeeeeeeeeerf Laboratory Findings: ? Fasting glucose: 165 mg/dL ? HbA1c: 8.2% ? Urinalysis: Positive for glucose, negative for ketones Diagnosis: Type 2 Diabetes Mellitus Questions and Answers:
1. What is the primary pathophysiological mechanism in type 2 diabetes?
2. Why is the patient experiencing increased thirst and frequent urination?
3. What is the significance of an HbA1c of 8.2%? Need Assignment Help?
4. Why is the patient's urinalysis positive for glucose but negative for ketones?
5. How does obesity contribute to the development of type 2 diabetes?