Extra-cellular signals
You are given a mutant cell which lacks the GTPase activating protein. What are the abnormalities would one expect to find out in the way which RAS activity responds to extra-cellular signals? Explain why?
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Purine biosynthesis is permitted to occur in the presence of [N15] aspartate, and the newly synthesized GTP and ATP are isolated. What are the positions which are labeled in the two nucleotides?
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