Explain triose phosphate isomerase catalyzes the conversion of dihydroxyacetone -P to glyceraldehyde-3-P. The standard free energy change, D G°', for this reaction is +7.6 kJ/mol. Thus the observed free energy change (D G) for the reaction in erythrocytes is +2.4 kJ/mol.
a. Compute the ratio of [dihydroxyacetone -P] / [glyceraldehyde-3-P] in erythrocytes from D G.
b. If [dihydroxyacetone -P] = 0.2 mM, what is [glyceraldehyde - 3-P]?