Problem:
Q1. Is there any missing information from the initial post?
Q2. What is one additional diagnostic test or treatment option that you would add for this patient?
Q3. What is one thing that you learned from reading this post? Need Assignment Help?
This discussion looks into the case of a 38-year-old patient with a reported history of asthma. The patient showed symptoms such as angioedema, hives, wheezing and tachycardia. With this in mind, the discussion seeks to establish genetic mutations consistent with the disease. The post will also discuss the symptoms, the pathophysiological mechanisms of the disease and what the blood test reveals. Genetic Mutations Recurrent anaphylaxis can be an indication of mast-cell activation abnormalities. Genetic abnormalities include the KIT D816V mutation, which occurs in reported cases of idiopathic anaphylaxis (González de Olano et al., 2023). It leads to increased abnormal activities in the mast cells. Another mutation is hereditary alpha-tryptasemia, which can be seen in recurrent anaphylaxis. Asthma-related genes also could undergo mutation. The fact that the patient has a history of asthma could point to a mutation of related cells. Symptoms Angioedema and hives are caused by histamine. Immune responses in the form of histamine lead to allergic reactions.