Describe the molecular mechanism of the development of


Ms. Blake is an older adult withdiabetesand has been too ill to get out of bed for 2 days. She has had asevere cough and has been unable to eat or drinkduring this time. She has ahistory of Type I diabetes. On admission her laboratory values show:

Sodium (Na+)

156 mEq/L

Potassium (K+)

4.0 mEq/L

Chloride (Cl-)

115 mEq/L 106 high

Arterial blood gases (ABGs)

pH- 7.30; Pco2-40;Po2-70;80-100 L

HCO3-20 (22-28) low



Normal values


Sodium (Na+)

136-146 mEq/L

Potassium (K+)

3.5-5.1 mEq/L

Chloride (Cl-)

98-106 mEq/L

Arterial blood gases (ABGs)

pH- 7.35-7.45

Pco2- 35-45 mmHg

Po2-80-100 mmHg

HCO3-22-28 mEq/L

  • List five (5) reasons on why she may have become bed ridden?
  • Based on these reasons what tests would you order?
  • Describe the molecular mechanism of the development of ketoacidosis.

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Biology: Describe the molecular mechanism of the development of
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