Describe the carcinogenesis phase when a tumor metastasizes


Assignment: Cancer & Diagnosis

J.C is an 82-year-old white man who was evaluated by GI specialist due to abdominal discomfort, loss of appetite, weight lost, weakness and occasional nausea.

Past Medical History (PMH):

Patient is Diabetic, controlled with Metformin 500 mg by mouth twice a day, Lantus 15 units SC bedtime. Hypertensive, controlled with Olmesartan 20 mg by mouth once a day. Atrial Fibrillation, controlled with Rivaroxaban 15 mg by mouth once a day and bisoprolol 10 mg by mouth once a day.

Labs:

Hb 12.7 g/dl; Hct 38.8% WBC 8.2; Glycemia 74mg/dl; Creatinine 0.8 mg/dl; BUN 9.8 mg/dl; AST 21 U/L ALT 17 U/L; Bil T 1.90 mg/dl; Ind 0.69 mg/dl; Dir 1.21 mg/dl.

Diagnostic test:

Endoscopic Ultrasound of the Pancreas. Solid mass in the head of pancreas 4 cms, infiltrating Wirsung duct. The solid mass impress to infiltrate the superior mesenteric vein. Perilesional node is detected, 1.5 cms, metastatic aspect. Fine needle aspiration (FNA) biopsy: Ductal adenocarcinoma.

Case study questions:

• Name the potential most common sites for metastasis on J.C and why?

• What are tumor cell markers and why tumor cell markers are ordered for a patient with pancreatic cancer?

• Based on the case study described, proceed to classify the tumor based on the TNM Stage classification. Why this classification important?

• Discussed characteristic of malignant tumors regarding it cells, growth and ability to spread.

• Describe the carcinogenesis phase when a tumor metastasizes.

• Choose the tissue level that is affected on the patient discussed above: Epithelial, Connective, Muscle or Neural. Support your answer.

Format your assignment according to the give formatting requirements:

• The answer must be using Times New Roman font (size 12), double spaced, typed, with one-inch margins on all sides.

• The response also includes a cover page containing the student's name, the title of the assignment, the course title, and the date. The cover page is not included in the required page length.

• Also include a reference page. The references and Citations should follow APA format. The reference page is not included in the required page length.

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