A superantigen is a bacterial product


A superantigen is a bacterial product that

binds to B7 and CD28 costimulatory molecules

binds to the beta chain of TCR and MHC class II molecules of APC stimulating T cell activation

binds to the CD4 + molecule causing T cell activation

is presented by macrophages to a larger-than-normal number of T helper CD4 + lymphocytes

stimulates massive amounts of IgG synthesis because of its large size

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