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Treatment of hemophilia

Illustrate out the treatment of hemophilia? Why hemophilia uncommon in females?

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Hemophilia is medically treated with administration of a factor VIII, in the case of hemophilia A, or of factor IX, in the case of hemophilia B, by means of the blood or the fresh frozen plasma transfusions.

Hemophilia, A or B, is X-linked recessive inheritance and for a girl to be hemophilic it is essential for both of her X chromosomes to be influenced while boys, which have only one X chromosome, are more easily influenced.

A girl with only one influenced chromosome doesn’t present the disease because the normal gene of the uninfluenced other X chromosome produces clotting factor.

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