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Physiological reason of syndrome acknowledged as cretinism

What is the physiological reason of the syndrome acknowledged as cretinism?

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Cretinism is caused because of chronic deficiency of thyroid hormones (T3 &T4) during babyhood. The constant hypothyroidism throughout childhood can cause retardation and low build due to the low basal metabolic rate in a stage of life when expansion and development of mind faculties occur.

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