Phenomenon to decrease neurotransmitters

Question

As neurotransmitters are not consumed in the synaptic process, specify the phenomenon in order to decrease their concentrations in the synaptic cleft after they have been used?

Answer 1

As binding of neurotransmitters to the postsynaptic receptors is reversible, after these neurochemicals perform their role they should be removed from the synaptic cleft. Neurotransmitters, then bind to the specific proteins that carry them back to the axon they came from in a process known as neurotransmitter re-uptake. They may also be destroyed through the specific enzymes, such as acetylcholinesterase, an enzyme which destroys acetylcholine. Or they may simply diffuse out of synaptic cleft.