Elucidate mitotic apparatus
Elucidate mitotic apparatus?
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Mitotic apparatus is the set of aster fibers, radial structures about each centriole pair, in addition the spindle fibers, fibers which extend across the cell among two centriole pairs situated in opposite cell poles. The mitotic apparatus emerges in prophase and has significant role in the orientation and gripping of chromosomes and other cellular elements causing them to detach and migrate to opposite cell poles.
Substances which disallow the formation of mitotic apparatus, such as colchicine, a molecule which binds to tubulin molecules and saves the synthesis of microtubules, interrupt cell division. Colchicine is employed to study chromosomes as it paralyzes mitosis whenever chromosomes are condensed and therefore are more simply viewed under the microscope.
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