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Phylogenetic tree by using upgma method

Question 1: Find out the sequence weights for the sequences ACTA, ACTT, CGTT and AGAT by using Thompson, Higgins and Gibson method

a) Compute pair wise distances between the sequences.
b) Build phylogenetic the tree by using UPGMA method.
c) Derive sequence weights.

Question 2: We supposed additive property when constructed UPGMA tree in question 1. What is limitation of this supposition?

Question 3: The sequence of gene ‘B3’ was used to blast against swissprot protein database. The query returned five significant hits to the other proteins denoted by B1, B2, B4, B5 and H in the figure shown below. B1-B5 is five bacterial species, while the species H represents Homo sapiens. No other mammalian species have shown presence of protein that is similar to B3. Describe the presence of this gene in the humans.

1001_protein database.jpg

Problem 4: Explain technical and theoretical challenges related with building phylogenetic trees.

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Biology: Phylogenetic tree by using upgma method

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The task pertains to solving the assignment based on the knowledge of genetic species and their evolution. Only question 3 and 4 have been answered as required by the client. The same has been specifically asked by the client in his/her message. The solution has been accurately analysed and the references for the same has also been included.

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Biology: Phylogenetic tree by using upgma method

Reference No:- TGS01348

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Biology: Phylogenetic tree by using upgma method

Reference No:- TGS01348

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