Explain issues regarding the immutability of the data


Problem:

This is mainly a follow-up question to the recent paper Next-Generation Digital Information Storage in DNA.
Personally, while I agree about the data density of the format, I can't help point out the large issues with the inability to rewrite and recopy the data efficiently and potential issues regarding the "immutability" of the data. I'm curious about other takes on the publication and whether or not the stability of the DNA as well as the "writing" inefficiencies are better than I'm believing.

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Biology: Explain issues regarding the immutability of the data
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