Significance of Krebs cycle

Significance of Krebs cycle:

Two molecules of acetyl CoA enter into Krebs cycle that on subsequent oxidation produce 6NADH2, 2FADH2. While 6NADH2, 2FADH2 enter into the electron transport system produce 22ATP molecules. In one step, there is substrate level phosphorylation that directly yields 2ATP molecules. Thus, throughout Krebs cycle, each 2 molecules of acetyl CoA enter into Krebs cycle 24 ATP molecules are produced. Thus, mainly it is an energy producing system. Because, Krebs cycle includes with both anabolic and catabolic processes, it is al well explained like a amphibolic process.


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