Action mechanism of antiretroviral drugs
Write down the action mechanism of antiretroviral drugs called protease inhibitors which are employed against HIV infection?
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Protease inhibitors are some of antiretroviral drugs which are used to treat HIV infection. Protease is enzyme essential for the assembling of HIV after the synthesis of its proteins within the host cell. The protease inhibitor binds to the activation center of the enzyme blocking the formation of the enzyme-substrate complex and the enzyme activity thus impairing the viral replication.
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Pharmacodynamics is the study of therapeutic value of drugs on the body. A graphical explanation of the Pharmacokinetics and Pharmacodynamics is given in Lapham and is reproduced here. Q : Speed of the enzymatic reactions How How does the substrate concentration influence the speed of the enzymatic reactions?
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