The Tell-Tale Heart by Edgar Allan Poe
Where does the story take place?
What does the setting suggest about the characters' lives?
Are there significant differences in the settings for different characters? What does this suggest about each person?
When does the story take place? Is the time of year or time of day significant?
Does the weather play a meaningful role in the story's action?
What is the protagonist's relationship to the setting?
Does the setting of the story in some way compel the protagonist into action?
Does the story's time or place suggest something about the character of the protagonist?
Does a change in setting during the story suggest some internal change in the protagonist?