Give examples of an intrinsic trigger for apoptosis

Question

Problem:

Question 1: Which of the following statement(s) is/are true about caspases?

1. Caspases cleave other proteins.
2. Cleavage by caspases can either destroy or activate a protein.
3. Caspases are one of the features of apoptosis that are often conserved among many species of organism.
4. All answers are correct.
5. All answers are incorrect.

Question 2: Which of the following is/are an example of an intrinsic trigger for apoptosis?

1. damaged DNA
2. mitochondrial damage
3. a ligand binding to the death receptor
4. All answers are correct.
5. damaged DNA and mitochondrial damage only

 

Question 3: Complete the following sentence: When a tissue is injured by a toxin and cells die, followed by immune system stimulation, this process is called...

1. programmed cell death
2. necrosis
3. a caspase activation cascade
4. autophagy
5. apoptosis

 

Question 4: Complete the following sentence: A drug that enhances the apoptotic response might be considered as a therapy for...

1. human cancer
2. Huntington's disease
3. Alzheimer's disease
4. All answers are correct.
5. All answers are incorrect

Provide the correct answer and justification for your choice.