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Find a long running prospective study in the us framingham

Find a long running prospective study in the US (Framingham, WHI, NHS, Rancho Bernardo, etc.) and highlight at least 3 separate major findings that have come out of the study. Discuss the impact of the prospective study and its findings. What major challenges are faced by longitudinal studies (think "lost to follow-up")? What is a couple of different ways that studies can address lost to follow-up?

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