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Relation between the thyroid and hypophysis

Describe the relation between the thyroid and hypophysis?

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The hypophysis secretes TSH, that is, thyroid-stimulating hormone. This hormone hastens the secretion of thyroid hormones (or triiodothyronine and thyroxine, or T3 and T4).

Whenever the plasma concentration of thyroid hormones is very high, this information is detected by the hypothalamus and by hypophysis and this gland decreases the TSH secretion. Whenever the thyroid hormone levels are low, the TSH secretion rises. It is therefore a negative feedback.

Injuries of hypophysis which cause TSH hyposecretion (for illustration, in case of tissue destruction) or hypersecretion (in case, example: of excessive cell proliferation or cancer) can modify the functioning of thyroid gland totally.

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